Too much scarring makes it harder for your liver to do its job. Whenever your liver is harmed, it attempts to heal itself. It can result from several conditions such as hepatitis (an inflammatory disease) or alcohol abuse.Īutoimmune diseases of the liver such as autoimmune hepatitis, primary sclerosing cholangitis, and primary biliary cholangitis also are causes of cirrhosis and portal hypertension. The main cause of portal hypertension is cirrhosis.
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